Heparin Other characteristics of the blood

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Heparin
Other characteristics of the blood are heparin, which is injected or implanted. If he has been activated and received the so-called preventive injection by coagulation after the operation, it is likely to be heparin. Heparin acts differently than anti-vitamin K. It accelerates the action of anticoagulants (antithrombin).

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But you can also use ASA (for example, aspirin) to relieve blood. This blood thinning group suppresses the function of platelets, so it can not meet well.

Oral anticoagulants
A relatively new group of anticoagulant medications is called direct oral anticoagulants. These blood sprays directly prevent coagulation Gethealthyfreedom factors. Although they have not been commercialized since 2008, they are often described.

Blutverdünner – billions of market despite the side effects
Direct oral anticoagulants also include rivaroxaban, finer blood and Bayer’s best sellers. It is in the market as Xarelto® and currently contributes 2 billion euros to Bayer every year, but not in an indisputable way.

First, anticoagulants were approved only to prevent the clot. But this market is quite small. Therefore, the Phase III study was conducted on more than 15,000 elderly patients to show that Xarelto® was not worse than warfarin. The treatment was present and approved in 2010 for the prevention of cerebrovascular accidents, a market worth 20 billion euros.

In 2011, Bayer was able to sell 0.7 million doses per day (only in Germany). One year later, there were 25.5 million daily doses, a sign of the great experience of Bayer’s marketing department, but not for compliance without restrictions.

Already in 2012, the Federal Institute for Drugs and Medical Devices (BfArM) received 750 reports of negative comments from Xarelto®, including 58 deaths. In the first eight months of 2013, there were 968 negative events with 72 deaths, Spiegel reported at the time.

Of course, both BfArM and Bayer showed a causal relationship away from themselves. So it’s just a coincidence, is not it?

Anticoagulants – side effects
Anticoagulants are known for their side effects. The main problem is the hard dose, which must be determined individually for each individual. Gethealthyfreedom Therefore, some time is needed to “adjust” the correct dose. Even in this case the situation can change again and again.

For this reason, many patients with coumarin should go to the doctor at least once a month to register. Another part of the patient is able to control the ability of blood coagulation (INR value) independently in the home with a device to measure and adjust the dose of the medication accordingly.

The average international rate (INR) is approximately 1 or less in healthy individuals.

If the value increases without taking anticoagulants, there is a health problem. B. Vitamin K deficiency. Because vitamin K regulates blood clotting. If missing, it leads to bleeding disorders.

If it is necessary to reduce the blood now by treatment (to prevent coagulation and clots), then the volume of diluted blood increases so that the INR increases from 2 to 3. In some cases, the risk of stroke is particularly high, the value increases from 3.5 to 4.5.

Therefore, the value obtained by the drug differs significantly from the adequate blood value. The blood is more “diluted” than with the right blood. What’s the score?

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